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perhexiline (maleate) (Cayman Chemical)

Name: perhexiline (maleate)
Brand: Cayman Chemical
Rating: 90 (1 reviews)

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Cayman Chemical perhexiline (maleate)

( A ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t test (10 μM vs. control, P = 0.2519; 50 μM vs. control, P = 0.0042; 100 μM vs. control, P = 0.0087; 200 μM vs. control, P = 2.42 × 10 −5 ). n.s. no significance. Scale bar, 50 μm. ( B ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Oxfenicine. Error bars represent mean ± s.e.m. with n = 3 replicates. * P < 0.05, *** P < 0.001; two tailed, unpaired Student’s t test. For Ki67 + /Pax7 + percentage, 2.5 mM vs. control, P = 0.13; 10 mM vs. control, P = 0.0187. For cell count (%), 2.5 mM vs. control, P = 0.00016; 10 mM vs. control, P = 7.97 × 10 −7 ; 2.5 mM vs. 10 mM, P = 0.00017; n.s. no significance. Scale bar, 50 μm. ( C ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or <t>Perhexiline.</t> Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For Ki67 + /Pax7 + percentage, 2.5 μM vs. control, P = 0.00049; 5 μM vs. control, P = 0.00231; For cell count (%), 2.5 μM vs. control, P = 0.00011; 5 μM vs. control, P = 7.43 × 10 −5 ; 2.5 μM vs. 5 μM, P = 0.0037. Scale bar, 50 μm.

Perhexiline (Maleate), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/perhexiline (maleate)/product/Cayman Chemical
Average 90 stars, based on 1 article reviews

perhexiline (maleate) - by Bioz Stars, 2026-02

90/100 stars

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1) Product Images from "Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation"

Article Title: Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

Journal: The EMBO Journal

doi: 10.1038/s44318-025-00397-1

Figure Legend Snippet: ( A ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t test (10 μM vs. control, P = 0.2519; 50 μM vs. control, P = 0.0042; 100 μM vs. control, P = 0.0087; 200 μM vs. control, P = 2.42 × 10 −5 ). n.s. no significance. Scale bar, 50 μm. ( B ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Oxfenicine. Error bars represent mean ± s.e.m. with n = 3 replicates. * P < 0.05, *** P < 0.001; two tailed, unpaired Student’s t test. For Ki67 + /Pax7 + percentage, 2.5 mM vs. control, P = 0.13; 10 mM vs. control, P = 0.0187. For cell count (%), 2.5 mM vs. control, P = 0.00016; 10 mM vs. control, P = 7.97 × 10 −7 ; 2.5 mM vs. 10 mM, P = 0.00017; n.s. no significance. Scale bar, 50 μm. ( C ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Perhexiline. Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For Ki67 + /Pax7 + percentage, 2.5 μM vs. control, P = 0.00049; 5 μM vs. control, P = 0.00231; For cell count (%), 2.5 μM vs. control, P = 0.00011; 5 μM vs. control, P = 7.43 × 10 −5 ; 2.5 μM vs. 5 μM, P = 0.0037. Scale bar, 50 μm.

Techniques Used: Immunofluorescence, Control, Two Tailed Test, Cell Counting

( A ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 4–6 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For differentiation index, 50 μM vs. control, P = 0.0057; 100 μM vs. control, P = 0.0013. For fusion index, 50 μM vs. control, P = 0.0021; 100 μM vs. control, P = 0.00032. Scale bar, 500 μm (top); 100 μm (bottom). ( B ) Immunoblots showing relative levels of MF20 and Cpt2 in primary myoblasts treated with vehicle control or Etomoxir (50 µM). ( C ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Perhexiline (5 µM) and Oxfenicine (2.5 mM). Error bars represent mean ± s.e.m. with n = 3–6 replicates. * P < 0.05, ** P < 0.01; two tailed, unpaired Student’s t test. For differentiation index, Perhexiline vs. control, P = 0.0472; Oxfenicine vs. control, P = 0.012. For fusion index, Perhexiline vs. control, P = 0.0025; Oxfenicine vs. control, P = 0.01052. Scale bar, 200 μm (top); 100 μm (bottom).

Figure Legend Snippet: ( A ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 4–6 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For differentiation index, 50 μM vs. control, P = 0.0057; 100 μM vs. control, P = 0.0013. For fusion index, 50 μM vs. control, P = 0.0021; 100 μM vs. control, P = 0.00032. Scale bar, 500 μm (top); 100 μm (bottom). ( B ) Immunoblots showing relative levels of MF20 and Cpt2 in primary myoblasts treated with vehicle control or Etomoxir (50 µM). ( C ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Perhexiline (5 µM) and Oxfenicine (2.5 mM). Error bars represent mean ± s.e.m. with n = 3–6 replicates. * P < 0.05, ** P < 0.01; two tailed, unpaired Student’s t test. For differentiation index, Perhexiline vs. control, P = 0.0472; Oxfenicine vs. control, P = 0.012. For fusion index, Perhexiline vs. control, P = 0.0025; Oxfenicine vs. control, P = 0.01052. Scale bar, 200 μm (top); 100 μm (bottom).

Techniques Used: Immunofluorescence, Control, Two Tailed Test, Western Blot

Figure Legend Snippet: Reagents and tools table

Techniques Used: Produced, Ex Vivo, In Vitro, Sequencing, Red Blood Cell Lysis, Modification, Saline, Blocking Assay, Plasmid Preparation, Protease Inhibitor, Reverse Transcription, Isolation, Bicinchoninic Acid Protein Assay, Western Blot, In Situ, Fluorescence, Detection Assay, TUNEL Assay, Software, Microscopy, Mass Spectrometry, Liquid Chromatography

Image Search Results

Journal: The EMBO Journal

Article Title: Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

doi: 10.1038/s44318-025-00397-1

Figure Lengend Snippet: ( A ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t test (10 μM vs. control, P = 0.2519; 50 μM vs. control, P = 0.0042; 100 μM vs. control, P = 0.0087; 200 μM vs. control, P = 2.42 × 10 −5 ). n.s. no significance. Scale bar, 50 μm. ( B ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Oxfenicine. Error bars represent mean ± s.e.m. with n = 3 replicates. * P < 0.05, *** P < 0.001; two tailed, unpaired Student’s t test. For Ki67 + /Pax7 + percentage, 2.5 mM vs. control, P = 0.13; 10 mM vs. control, P = 0.0187. For cell count (%), 2.5 mM vs. control, P = 0.00016; 10 mM vs. control, P = 7.97 × 10 −7 ; 2.5 mM vs. 10 mM, P = 0.00017; n.s. no significance. Scale bar, 50 μm. ( C ) Ki67 immunofluorescence (green) and quantification of percentages of Ki67 + primary myoblasts treated with vehicle control or Perhexiline. Error bars represent mean ± s.e.m. with n = 6–9 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For Ki67 + /Pax7 + percentage, 2.5 μM vs. control, P = 0.00049; 5 μM vs. control, P = 0.00231; For cell count (%), 2.5 μM vs. control, P = 0.00011; 5 μM vs. control, P = 7.43 × 10 −5 ; 2.5 μM vs. 5 μM, P = 0.0037. Scale bar, 50 μm.

Article Snippet: Perhexiline (maleate) , Cayman Chemical , Cat# 16982.

Techniques: Immunofluorescence, Control, Two Tailed Test, Cell Counting

Journal: The EMBO Journal

Article Title: Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

doi: 10.1038/s44318-025-00397-1

Figure Lengend Snippet: ( A ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Etomoxir. Error bars represent mean ± s.e.m. with n = 4–6 replicates. ** P < 0.01, *** P < 0.001; two tailed, unpaired Student’s t -test. For differentiation index, 50 μM vs. control, P = 0.0057; 100 μM vs. control, P = 0.0013. For fusion index, 50 μM vs. control, P = 0.0021; 100 μM vs. control, P = 0.00032. Scale bar, 500 μm (top); 100 μm (bottom). ( B ) Immunoblots showing relative levels of MF20 and Cpt2 in primary myoblasts treated with vehicle control or Etomoxir (50 µM). ( C ) Immunofluorescence of MyoG (red) and MF20 (green) and quantification of differentiation and fusion index in primary myoblasts treated with vehicle control or Perhexiline (5 µM) and Oxfenicine (2.5 mM). Error bars represent mean ± s.e.m. with n = 3–6 replicates. * P < 0.05, ** P < 0.01; two tailed, unpaired Student’s t test. For differentiation index, Perhexiline vs. control, P = 0.0472; Oxfenicine vs. control, P = 0.012. For fusion index, Perhexiline vs. control, P = 0.0025; Oxfenicine vs. control, P = 0.01052. Scale bar, 200 μm (top); 100 μm (bottom).

Article Snippet: Perhexiline (maleate) , Cayman Chemical , Cat# 16982.

Techniques: Immunofluorescence, Control, Two Tailed Test, Western Blot

Journal: The EMBO Journal

Article Title: Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation

doi: 10.1038/s44318-025-00397-1

Figure Lengend Snippet: Reagents and tools table

Article Snippet: Perhexiline (maleate) , Cayman Chemical , Cat# 16982.

Techniques: Produced, Ex Vivo, In Vitro, Sequencing, Red Blood Cell Lysis, Modification, Saline, Blocking Assay, Plasmid Preparation, Protease Inhibitor, Reverse Transcription, Isolation, Bicinchoninic Acid Protein Assay, Western Blot, In Situ, Fluorescence, Detection Assay, TUNEL Assay, Software, Microscopy, Mass Spectrometry, Liquid Chromatography

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1) Product Images from "Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation"

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